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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNPC3 All Species: 16.06
Human Site: S121 Identified Species: 27.18
UniProt: Q96LT9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96LT9 NP_060089.1 517 58575 S121 G S E K K K R S D D P V E D D
Chimpanzee Pan troglodytes XP_524780 517 58585 S121 G S E K K K R S D D P V E D D
Rhesus Macaque Macaca mulatta XP_001108341 447 50381 P111 D Q V H S P C P T S G S E K K
Dog Lupus familis XP_547257 729 81274 S333 D P E K K K R S D D P V E D D
Cat Felis silvestris
Mouse Mus musculus Q3UZ01 514 57954 L121 N T E K K K R L D D T V E N D
Rat Rattus norvegicus Q4G055 515 58019 L121 N A E K K K R L D D T V E N D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509729 515 58068 S125 P T E K S K R S E E P V E E E
Chicken Gallus gallus XP_422302 550 62756 S158 F S D K Y K S S E E P V K E E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001035019 505 56850 K118 A E K E K K E K Q Q P S V P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623250 403 46802 H68 T E A L L R L H Q L N V K G Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783188 518 57780 M120 D M Q T K R I M K T I G M A P
Poplar Tree Populus trichocarpa XP_002325403 420 46033 L85 V D F K S E S L A Y Q A H T Q
Maize Zea mays NP_001132325 450 49544 G115 L K H Q D Q L G H G A S Q V P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172394 442 48694 K107 A N K P N D N K K S R Q I E E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 83.1 66.1 N.A. 88.7 88 N.A. 72.1 66.9 N.A. 56.4 N.A. N.A. 33.4 N.A. 40.5
Protein Similarity: 100 99.8 83.3 68.1 N.A. 93.2 92.6 N.A. 82.7 78 N.A. 71.1 N.A. N.A. 48.5 N.A. 58.6
P-Site Identity: 100 100 6.6 86.6 N.A. 66.6 66.6 N.A. 53.3 40 N.A. 20 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 100 6.6 86.6 N.A. 80 80 N.A. 86.6 80 N.A. 33.3 N.A. N.A. 20 N.A. 20
Percent
Protein Identity: 28 30.9 N.A. 32.8 N.A. N.A.
Protein Similarity: 42.5 47.7 N.A. 47.9 N.A. N.A.
P-Site Identity: 6.6 0 N.A. 0 N.A. N.A.
P-Site Similarity: 13.3 20 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 8 0 0 0 0 0 8 0 8 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 22 8 8 0 8 8 0 0 36 36 0 0 0 22 36 % D
% Glu: 0 15 43 8 0 8 8 0 15 15 0 0 50 22 22 % E
% Phe: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 0 0 0 0 0 0 8 0 8 8 8 0 8 0 % G
% His: 0 0 8 8 0 0 0 8 8 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 8 0 8 0 0 % I
% Lys: 0 8 15 58 50 58 0 15 15 0 0 0 15 8 8 % K
% Leu: 8 0 0 8 8 0 15 22 0 8 0 0 0 0 8 % L
% Met: 0 8 0 0 0 0 0 8 0 0 0 0 8 0 0 % M
% Asn: 15 8 0 0 8 0 8 0 0 0 8 0 0 15 0 % N
% Pro: 8 8 0 8 0 8 0 8 0 0 43 0 0 8 15 % P
% Gln: 0 8 8 8 0 8 0 0 15 8 8 8 8 0 15 % Q
% Arg: 0 0 0 0 0 15 43 0 0 0 8 0 0 0 0 % R
% Ser: 0 22 0 0 22 0 15 36 0 15 0 22 0 0 0 % S
% Thr: 8 15 0 8 0 0 0 0 8 8 15 0 0 8 0 % T
% Val: 8 0 8 0 0 0 0 0 0 0 0 58 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _